Chronic viral hepatitis is a syndrome characterized by hepatotropic viral infection usually associated with chronic inflammation, hepatocyte injury and progressive fibrosis, that can progress to cirrhosis and associated complications. Hepatitis becomes chronic when infection lasts more than 6 months, typically in the context of HCV or HBV.
There are strong correlations of liver stiffness with liver fibrosis in Hepatitis C, Hepatitis B, and also in other causes of liver disease such as MASLD and MASH.
Before VCTE™ and CAP™, the only real diagnostic option for assessing patients with hepatitis C virus was biopsy, and even then, we couldn’t always pick up ‘borderline’ cases. We’ve almost stopped doing biopsies now, except in rare diagnostic dilemmas.
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