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FibroScan® powered by CAP™

CAP™ is the non-invasive reference parameter to diagnose and monitor liver steatosis.  

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Liver steatosis, why quantify it?

There is a silent epidemic of fatty liver disease in the general population, called MASLD/MASH. The main causes of fatty liver disease are excessive alcohol consumption and/or poor diet and sedentary lifestyle.

If patients remain undiagnosed and untreated, they may go on to develop irreversible cirrhosis of the liver. If treated early with diet and lifestyle changes, the disease can be reversible.

Who is at-risk of fatty liver disease?

Most patients with the presence of a metabolic syndrome.

Risk factors and predictors of MASLD

  • Type 2 diabetes 
  • Overweight and obesity
  • High cholesterol
  • High blood pressure
  • High triglycerides

Advantages of CAP™

CAP™ is unique, patented and validated for liver disease management1,2. 1,130 international and peer-reviewed articles support the use of CAP™.

CAP™ is a guiding point for doctors and patients to improve monitoring of lifestyle change and therapeutic intervention.

CAP™ is a quantitative surrogate of liver steatosis expressed in decibel per meter (db/m).

Both LSM by VCTE™ and CAP™ are measured simultaneously without lengthening the examination time.

CAP™ is available on the three FibroScan® probes (S+*, M+ and XL+).

CAP™: tried and trusted

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CAP™ provides a convenient and patient-friendly method to assess lipid turnover during lifestyle and dietary interventions to combat MASLD.

Publication Arslanow et al. | Clinical and Translational Gastroenterology, 2016

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Lifestyle modification improves the hepatic steatosis, and CAP™ can be used to detect the improvement of hepatic steatosis during follow-up in patients with MASLD on lifestyle modification.

Publication Paul et al. | Arq Gastroenterol, 2018

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The dietary intervention has a positive impact on CAP™.

Publication Arslanow et al. | Clinical and Translational Gastroenterology, 2016

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*CAP™ is not available on S probe in all countries.

1. Karlas T, Petroff D, Sasso M, et al. Individual patient data meta-analysis of controlled attenuation parameter (CAP) technology for assessing steatosis. J Hepatol. 2017;66(5):1022-1030. doi:10.1016/j.jhep.2016.12.022.
2. Recio E, Cifuentes C, Macías J, et al. Interobserver concordance in controlled attenuation parameter measurement, a novel tool or the assessment of hepatic steatosis on the basis of transient elastography. Eur J Gastroenterol Hepatol. 2013;25(8):905-911.doi:10.1097/MEG.0b013e32835f4c3d.

Indications for use

The Shear wave speed and stiffness measurements may be used as an aid to clinical management of adult patients with liver disease. 
The shear wave speed and stiffness, and CAP may be used as an aid to diagnosis and monitoring of adult patients with liver disease, as part of an overall assessment of the liver. Shear wave speed and stiffness, and CAP* may be used as an aid in the clinical management of pediatric patients with liver disease.

* CAP for pediatric patients with liver disease is only available with SmartExam capability.